2010

Beckham JT, Wilmink GJ, Mackanos MA, Takahashi K, Contag CH, Takahashi T, Jansen ED – Role of hsp70 in cellular thermotolerance – Lasers Surg Med (in press).

Cayce JM, Kao CC, Malphrus JD, Konrad PE, Mahadevan-Jansen A, Jansen ED – Infrared Neural Stimulation of Thalamocortical Brain Slices – IEEE J Spec Topics Quantum Electr 16(3): 565-72 (2010).

Cayce JM, Wells JD, Malphrus JD, Kao CC, Thomsen S, Tulipan NB, Konrad PE, Jansen ED, Mahadevan-Jansen A. Advancing infrared neural stimulation towards use in humans. Nature Medicine (submitted).

Feng HJ, Kao CC, Gallagher MJ, Jansen ED, Mahadevan-Jansen A, Konrad PE, MacDonald RL – Alteration of GABAergic neurotransmission by pulsed infrared laser stimulation – J Neural Engineering (in press).

Jenkins M.W., Duke A.R., Gu S., Chiel H.J., Watanabe M., Jansen E.D., Rollins A.M. “Optical pacing of the embryonic heart,” Nature Photonics, Aug 15, doi:10.1038/nphoton.2010.166 (2010).

Makowski AJ, Davidson JM, Mahadevan-Jansen A, Jansen ED – Raman spectroscopic analysis of the role of Hsp70 and laser preconditioning on incisional wound healing in vivo – Lasers Surg Med (submitted).

J. S. Nyman, C. C. Lynch, D. S. Perrien, S. Thiolloy, E. C. O’Quinn, C. A. Patil, X. Bi, G. M. Pharr, A. Mahadevan-Jansen, and G. R. Mundy, “Differential effects between the loss of MMP-2 and MMP-9 on structural and tissue-level properties of bone.” In preparation.

C. A. Patil, H. Krishnamoorthi, D. L. Ellis, T.G. Van Leeuwen, and A. Mahadevan-Jansen, “A Clinical Instrument for Combined Raman Spectroscopy-Optical Coherence Tomography of Skin Cancers” In preparation.

C. A. Patil, J. Kalkman, D. J. Faber, N. Bosschaart, J.S. Nyman, T.G. Van Leeuwen, and A. Mahadevan-Jansen, “Integrated System for Combined Raman Spectroscopy-Spectral Domain Optical Coherence Tomography,” submitted for publication in Optics Express

C. A. Patil, H. Krishnamoorthi, S. Munoz, G. Gutierrez, and A. Mahadevan-Jansen, “Rapid Measurement of Calvaria Volume and Biochemical Properties with Combined Raman Spectroscopy-Optical Coherence Tomography,” In preparation.

J.S. Nyman, T.P. Masui, C. A. Patil, X. Bi, E.C. O’Quinn, S.A. Guelcher, D.P. Nicollela, and A. Mahadevan-Jansen, “ Measuring Differences in Compositional Properties of Bone Tissue by Confocal Raman Specroscopy”, Under review for publication in Bone.

Richter CP, Matic AI, Wells J, Jansen ED, Walsh JT - Neural stimulation with optical radiation – Laser Photonic Rev, 1-13 / DOI 10.1002/lpor.200900044 (2010).

2009

Cayce JM, Kao CC, Konrad PE, Jansen ED, Mahadevan-Jansen A, Optical stimulation of thalamocortical brain slices, Journal of Neuroscience (in review), February 2009.

Duke AR, Cayce JM, Malphrus JD, Konrad P, Mahadevan-Jansen A,  Jansen ED – Combined optical and electrical stimulation of neural tissue in vivo – Journal of Biomedical Optics 14(6): 060501-3 (2009)

Granero-Moltó F, Weis JA, Miga MI, Landis B, Myers TJ, O'Rear L, Longobardi L, Jansen ED, Mortlock DP, Spagnoli A - Regenerative effects of transplanted mesenchymal stem cells in fracture healing - Stem Cells 27(8): 1887-98 (2009).

Kanter EM, Majumder SK, Kanter G, Woeste E, Mahadevan-Jansen A, Effect of hormonal variation on Raman spectra for cervical disease detection, American Journal of Obstetrics and Gynecology, 200(5), 512.e1, 2009.

Kanter EM, Vargis E, Majumder SK, Keller MD, Kanter GJ, Rao GG, Mahadevan-Jansen A, Application of Raman spectroscopy for diagnosis of cervical dysplasia (invited paper), Journal of Biophotonics, 2(1-2), 81-90, 2009.

Virostko J, Radhika A, Poffenberger G,Chen Z, Brissova M, Gilchrist J, Coleman B, Gannon M, Jansen ED, Powers AC - Bioluminescence imaging in mouse models quantifies β-cell mass in the pancreas and after islet transplantation – Mol Imaging and Biology, online: (doi:10.1007/s11307-009-0240-1), June (2009).

Wilmink GJ, Oalenik SR, Beckham JT, Abraham AA, Nanney LB, Mahadevan-Jansen A, Davdson JM, Jansen ED, Molecular imaging-assisted optimization of HSP70 expression during laser-induced thermal preconditioning for wound repair enhancement, Journal of Investigative Dermatology, 129(1), 205-216, 2009.

2008

Beckham JT, Wilmink GJ, Mackanos MA, Takahashi K, Contag CH, Takahashi T, Jansen ED – Role of hsp70 in cellular thermotolerance – Lasers Surg Med 40(10): 704-15 (2008).

Grimbergen M, van Swol CFP, van Moorselaar RJA, Mahadevan-Jansen A, Stone N, Effect of 5-ALA on the Raman spectra of bladder tissues, Journal of Photochemistry and Photobiology B (in press), December 2008.

Kanter EM, Vargis E, Majumder SK, Keller MD, Beaven RB, Rao GG, Mahadevan-Jansen A, Raman spectroscopy for cervical precancer detection. Gynecologic Oncology (in review), December 2008.

Keller MD, Kanter EM, Hutchings J, Kendal C, Stone N, Mahadevan-Jansen A, Spatial and temporal effects of cervical dysplasia as detected by Raman spectroscopy (invited paper), Disease Markers (in press), August 2008.

Lieber CA, Kanter EM, Mahadevan-Jansen A, Comparison of Raman spectrograph throughput using two commercial systems: transmissive versus reflective, Applied Spectroscopy, 62(5), 575-582, 2008.

Lieber CA, Majumder SK, Billheimer D, Ellis DL, Mahadevan-Jansen A, Raman microspectroscopy for skin cancer detection in vitro, Journal of Biomedical Optics, 13(2), epub: 024013, 2008.

Lieber CA, Majumder SK, Ellis DL, Billheimer D, Mahadevan-Jansen A, In vivo nonmelanoma skin cancer diagnosis using Raman microspectroscopy, Lasers in Surgery and Medicine, 40(7),461-467, 2008.

C. A. Patil, N. Bosschaart, M. D. Keller, T. G. van Leeuwen, and A. Mahadevan-Jansen, "Combined Raman spectroscopy and optical coherence tomography device for tissue characterization," Optics Letters, 33 (10), 1135-1137 (2008)  http://www.opticsinfobase.org/abstract.cfm?URI=ol-33-10-1135

Wilmink GJ, Opalenik SR, Beckham JT, Mackanos MA, Nanney LB, Contag CH, Davidson JM, Jansen ED –In-vivo optical imaging of hsp70 expression to assess collateral tissue damage associated with infrared laser ablation of skin – J Biomed Opt 13, 054066 (2008)

2007

Faley SL, Takahashi K, Crooke CE, Beckham JT, Tomemori T, Shappell SB, Jansen ED, Takahashi T - Bioluminescence imaging of vascular endothelial growth factor promoter activity in murine mammary tumorigenesis – In vivo bioluminescence imaging of VEGF promoter activity in transgenic mice – Mol Imaging 6(5):331-9 (2007)

Gebhart SC, Thompson RC, Mahadevan-Jansen A, Liquid-crystal tunable filter spectral imaging for brain tumor demarcation, Applied Optics, 46 (10): 1896-1910, 2007

Gebhart SC, Majumder SK, Mahadevan-Jansen A, Comparison of spectral variation from spectroscopy to spectral imaging, Applied Optics, 46 (8): 1343-1360, 2007.

Gorden DL, Fingleton B, Crawford HC, Jansen ED, Lepage M, Matrisian LM - Resident stromal cell-derived MMP-9 promotes the growth of colorectal metastases in the liver microenvironment – Intl J Cancer, April 6 (2007).

Izzo AD, Jansen ED, Richter CP, Walsh JT - Optical Parameter Variability in Laser Nerve Stimulation: a study of pulse duration, repetition rate, and wavelength – IEEE Transactions on Biomed Eng 54(6): (2007).

Lieber CA, Mahadevan-Jansen A, Development of a handheld Raman microspectrometer for clinical dermatologic applications, Optics Express, 15(19), 11874-11882, 2007.

Mackanos MA, Simanovskii D, Joos KM, Schwettman H, Jansen ED - Mid infrared optical parametric oscillator (OPO) as a viable alternative to tissue ablation with the free electron laser (FEL) – Lasers Surg Med 39(3): 230-6 (2007).

Majumder SK, Gebhart SC, Johnson MD, Thompson R, Lin WC, Mahadevan-Jansen A, A probability-based spectroscopic diagnostic algorithm for simultaneous discrimination of brain tumor and tumor margins from normal brain tissue, Applied Spectroscopy, 61 (5): 548-557, 2007 

Robichaux-Viehoever A, Kanter E, Shappell H, Billheimer D, Jones HW, Mahadevan-Jansen A, Characterization of Raman spectra measured in vivo for the detection of cervical dysplasia. Applied Spectroscopy, 61(9), 2007.

Toms SA, Lin WC, Weil R, Johnson MD, Jansen ED, Mahadevan-Jansen A - Intraoperative optical spectroscopy identifies infiltrating glioma margins with high sensitivity – Neurosurgery 61(1): 327-35 (2007)

Virostko J, Powers AC, Jansen ED - Validation of luminescent source reconstruction using single-view spectrally resolved bioluminescence images – Appl Optics 46(13): 2540-7 (2007).

Wells JD, Kao C, Konrad P, Milner T, Kim J, Mahadevan-Jansen A, Jansen ED, Biophysical mechanisms of transient optical stimulation of peripheral nerve, Biophysical Journal 93(7), 567-80, 2007

Wells JD, Kao C, Jansen ED, Konrad PE, Mahadevan-Jansen A, Histological Analysis of thermal damage following transient optical neural stimulation, Laser in Surgery and Medicine, 39(6), 519-26, 2007.

Wells JD, Konrad PE, Kao CC, Jansen ED, Mahadevan-Jansen A - Pulsed laser versus electrical energy for peripheral nerve stimulation – J Neurosci Methods 163: 326-37 (2007).

Wells JD, Thomsen SL, Whittaker P, Jansen ED, Kao CC, Konrad PE, Mahadevan-Jansen A - Histological analysis reveals safety thresholds for optical nerve stimulation – Lasers Surg Med 39(6): 513-26 (2007)

2006

Izzo AD, Richter CP, Jansen ED, Walsh JT - Laser Stimulation of the Auditory Nerve – Lasers Surg Med 38(7): 745-53 (2006).

Gebhart SC, Lin WC, Mahadevan-Jansen A, In vitro determination of normal and neoplastic human brain tissue optical properties using inverse adding-doubling, Physics in Medicine and Biology, 51 (8): 2011-2027, 2006.

Jansen ED, Pickett PM, Mackanos MA, Virostko JM - Effect of optical tissue clearing on spatial resolution and sensitivity of bioluminescence imaging – J Biomed Optics: 11:041119  (2006).

Jansen ED, Rastegar S – Pioneers in Biomedical Optics: Special Section Honoring Professor Ashley J. Welch, University of Texas at Austin, J Biomed Optics: 11: 041101 (2006).

Keller MD, Kanter EM, Mahadevan-Jansen A, Raman spectroscopy for cancer diagnosis, Spectroscopy (Cover), 21 (11): 33-41, 2006.

Moulton K, Lovell F, Williams E, Ryan P, Lay DC, Jansen ED, Willard S - Use of glycerol as an optical clearing agent for enhancing photonic transference and detection of Salmonella typhimurium through porcine skin – J Biomed Optics 11(5):05427 (2006).

Roth DJ, Jansen ED, Powers AC, Wang TG - A novel method of monitoring response to islet transplantation: bioluminescent imaging of an NF-kB transgenic mouse model – Transplantation 81(8): 1185-90 (2006).

Stevenson CB, Ehtesham M, Faley S, Cassady S, Jansen ED, Thompson RC – Development of quantum dot-based near-infrared molecular imaging for glioma – Neuro-Oncology 8(4): 489 (2006).

Virostko J, Jansen ED, Powers AC - Current status of imaging pancreatic islets - Current Diabetes Reports 6(4): 328–332 (2006).

Wells JD, Bendett M, Webb J, Ralph H, Kao C, Konrad PE, Mahadevan-Jansen A, Jansen ED, Lasers stimulate new techniques in nerve cells, International Biophotonics Journal (cover), Oct 2006.

Wilmink GJ, Opalenik SR, Beckham JT, Davidson JM, Jansen ED - Assessing laser-tissue damage with bioluminescent imaging – J Biomed Optics 11:041114 (2006). 

2005

C.A. Patil, E.D. Jansen, “Novel Optical Technologies to Aid Diagnosis and Guide Therapy in Colorectal Medicine,” Seminars in Colon and Rectal Surgery, 16 (2), 82-90 (2005).

Fowler M, Virostko J, Chen Z, Smith SJ, West DB, Poffenberger G, Radhika A, Brissova M, Shiota M, Nicholson, Hirschberg B, Harlan D, Jansen ED, Powers AC – Assessment of pancreatic islet mass after transplantation using in vivo bioluminescence imaging – Transplantation 79(7): 768-76 (2005).

Gebhart SC, Jansen ED, Galloway RL - Dynamic, three-dimensional optical tracking of an ablative laser beam - Medical Physics 32(1): 209-20 (2005). 

Gebhart, SC, Mahadevan-Jansen A, Lin, WC, Experimental and simulated angular profiles of fluorescence and diffuse reflectance emission from turbid media, Applied Optics, 44(23), 4884-4901, 2005

Lin WC, Johnson M, Weil RJ, Mahadevan-Jansen A, Toms SA, In vivo optical spectroscopic detection of radiation injury in brain tissue, Neurosurgery, 57(3), 518-524, 2005

Mackanos MA, Kozub JA, Hachey DL, Joos KM, Ellis DL, Jansen ED – The effect of free electron laser pulse structure on mid-infrared soft-tissue ablation: biological effects – Physics in Medicine and Biology 50(8): 1885-99 (2005).

Mackanos MA, Kozub JA, Jansen ED – The effect of free electron laser pulse structure on mid-infrared soft-tissue ablation: ablation metrics – Physics in Medicine and Biology 50(8): 1871-83 (2005).

M.R. Chalita, Y. Li, S. Smith, C. Patil, V. Westphal, A.M. Rollins, J.A. Izatt, and D. Huang. “High-Speed Optical Coherence Tomography of Laser Iridotomy” American Journal of Ophthalmology, 140 (6), 1133-1136. 2005.

Teichman JM, Glickman RD, Chan KF, Jansen ED, Welch AJ - Plasma bubble formation induced by holmium laser – Urology 65(3): 627-8 (2005).

Toms SA, Lin WC, Weil RJ, Johnson MD, Jansen ED, Mahadevan-Jansen A - Intraoperative optical spectroscopy identifies infiltrating glioma margins with high sensitivity – Neurosurgery 57(4): 382-91 (2005).

Wells JD, Kao C, Jansen ED, Konrad PE, Mahadevan-Jansen A, Assessment of laser parameters for optical stimulation of peripheral nerves in vivo, Journal of Biomedical Optics, 10(6), 064003 (E-journal Locator), 2005.

Wells JD, Kao C, Mariappan K, Albea J, Jansen ED, Konrad P, Mahadevan-Jansen A -  Optical stimulation of neural tissue in vivo - Optics Letters 30(5): 504-6 (2005).

2004

Anderson CD, Lin WC, Buttemere CR, Mahadevan-Jansen A, Phillips DJ, Pierce J, Nicoud I, Chari RS, Fluorescence spectroscopy accurately detects irreversible cell damage during hepatic radiofrequency ablation. Surgery, 136(3), 524-531, 2004

Anderson CD, Lin WC, Buttemere CR, Mahadevan-Jansen A, Phillips DJ, Pierce J, Nicoud I, Chari RS, Real-time spectroscopic assessment of thermal damage:  implications for radiofrequency ablation.  Journal of Gastrointestinal Surgery, 8(6), 660-669,2004.

Buttemere CR, Chari RS, Anderson CD, Mahadevan-Jansen A, Lin WC, “In vivo assessment of thermal damage in the liver using optical spectroscopy”, Journal of Biomedical Optics, 9(5), 1018-27, 2004

Beckham JT, Mackanos MA, Crooke C, Takahashi T, O’Conner-Rodwell CE, Contag CH, Jansen ED - Assessment of cellular response to thermal laser injury through bioluminescence imaging of hsp70 - Photochem Photobiol 79(1): 76-85 (2004). 

O’Connell-Rodwell CE, Shriver D, Simanovskii DM, McClure C, Cao Y, Zhang W, Bachmann MH, Beckham JT, Jansen ED, Palanker D, Schwettman HA, Contag CH - A genetic reporter of thermal stress defines physiologic zones over a defined temperature range – FASEB Journal 18:264-271 (2004). 

Powers AC, Jansen ED - In Vivo Bioluminescence Imaging to Assess Pancreatic Islets - Curr Med Chem 4(4): 339-48 (2004).

Sadikot RT, Zeng H, Yull FE, Li B, Cheng DS, Kernodle DS, Jansen ED, Contag CH, Segal BH, Holland SM, Blackwell TS, Christman JW - p47 (phox) deficiency impairs NF-kappa B activation and host defense in Pseudomonas pneumonia – J Immunology 172(3): 1801-8 (2004).

Virostko JM, Chen Z, Fowler M, Poffenberger G, Powers AC, Jansen ED - Factors influencing quantification of in vivo bioluminescence imaging: application to assessment of pancreatic islet transplants – J Mol Imaging 3(4): 333-42 (2004). 

2003

Choi B, Jansen ED, Welch AJ – Acoustic-based measurements of material absorption coefficients: Relationship between laser pulse duration and stress confinement time – J Appl Phys 94(12): 7826-31 (2003).

Edwards GS, Austin RH, Carroll FE, Copeland ML, Couprie ME, Gabella WE, Haglund RF, Hooper BA, Hutson MS, Jansen ED, Joos KM, Kiehart DP, Lindau I, Miao J, Pratisto HS, Shen JH, Tokutake Y, van der Meer L, Xie A - FEL-based biophysical and biomedical instrumentation (invited review paper) – Rev Sci Instr 74(7): 3207-45 (2003)

Gray KD, Simovic MO, Chapman WC, Blackwell TS, Christman JW, Washington MK, Yull FE, Jaffal N, Jansen ED, Gautman S, Stain SC – Systemic NF-kappaB activation in a transgenic mouse model of acute pancreatitis – J Surg Res 110(1): 310-4 (2003)

Lieber CA, Mahadevan-Jansen A, “Automated Method for Subtraction of Fluorescence from Biological Raman Spectra”, Applied Spectroscopy, 57(11), 1363-1367, 2003

Lin WC, Buttermere C, Mahadevan-Jansen A, “Effect of thermal damage on the optical characteristics of liver tissues”, IEEE Journal of Selected Topics in Quantum Electronics, 9(2), 162-170, 2003.

Mackanos MA, Shaw BL, Aggarwal, ID, Katzir A, Jansen ED - Delivery of Mid-Infrared (6-7 um) Laser Radiation in a Liquid Environment Using Infrared-Transmitting Optical Fibers - J Biomed Optics 8(4): 583-93 (2003).

Sadikot RT, Han W, Everhart MB, Zoia O, Peebles RS, Jansen ED, Yull FE, Christman JW, Blackwell TS - Selective I-κB kinase expression in airway epithelium generates Neutrophilic lung inflammation - J Immunology 170(2): 1091-8 (2003).

Viehoever AR, Anderson D, Jansen ED, Mahadevan-Jansen A - Organotypic raft cultures as an effective tool for understanding Raman spectral analysis of tissue - Photochemistry & Photobiology 78(5): 517-24 (2003)

Wu NJ, Jansen ED, Davidson JM - Comparison of MMP-13 Expression In Free-Electron Laser and Scalpel Incisions During Wound Healing - J of Investigative Dermatology 21(4): 926-32 (2003).

Yull FE, Han W, Jansen ED, Sadikot RT, Christman JW, Blackwell TS – Bioluminescent detection of endotoxin effects on HIV-1 LTR driven transcription in vivo - Journal of Histochemistry and Cytochemistry 51(6): 741-749 (2003)

2002

Chan KF, Choi B, Vargas G, Hammer DX, Sorg B, Pfefer TJ, Teichman JMH, Welch AJ, Jansen ED - Free electron laser ablation of urinary calculi: An experimental study - IEEE J Sp Top Quant Electr 7(6): 1022-33 (2002).

Lin WC, Toms SA, Jansen ED, Mahadevan-Jansen A – Intraoperative application of optical spectroscopy in the presence of blood, IEEE J Sp Top Quant Electr 7(6): 996-1003 (2002).

Sadikot RT, Wudel LJ, Jansen ED, Debelak JP, Yull FE, Christman JW, Blackwell TS, Chapman WC - Hepatic cryoablation-induced multisystem injury: bioluminescent detection of NF-kB activation in a transgenic mouse model - J Gastrointestinal Surg: 6: 264-270 (2002).

Wu N, Opalenik S, Liu J, Jansen ED, Giro MG, Davidson JM - Real-time visualization of MMP-13 promotor activity in transgenic mice - Matrix Biology 21:149-161 (2002).  

2001

Lin WC, Toms SA, Jansen ED, Mahadevan-Jansen A, Intraoperative application of optical spectroscopy in the presence of blood, IEEE Journal of Selected Topics in Quantum Electronics 7(6), 996-1003, 2001.

Lin WC, Toms SA, Johnson M, Jansen ED, Mahadevan-Jansen, A - In Vivo Brain Tumor Demarcation Using Optical Spectroscopy - Photochemistry and Photobiology: 73(4): 396-402 (2001).

Izzo AD, Mackanos MA, Beckham JT, Jansen ED - In vivo optical imaging of expression of vascular endothelial growth factor following laser incision in skin - Lasers Surg Med: 29(4):343-350 (2001).

Sadikot RT, Jansen ED, Blackwell TR, Zoia, O, Yull FE, Christman JW, Blackwell TS - High dose dexamethasone accentuates NF-B activation in endotoxin-treated mice - Am J Respir Crit Care Med: 164:873-878 (2001).

Utzinger U, Mahadevan-Jansen A, Hinzelman D, Follen M, Richards-Kortum R. Near infrared Raman spectroscopy for in vivo detection of cervical precancers, Applied Spectroscopy, 55(8), 2001

2000

Chan KF, Hammer DX, Choi B, Teichman JM, McGuff HS, Pratisto HS, Jansen ED, Welch AJ - Free Electron Laser lithotripsy: Threshold radiant exposures - Journal of EndoUrology 14(2):161-7 (2000).

Lin WC, Toms SA, Motamedi M, Jansen ED, Mahadevan-Jansen A - Brain  tumor demarcation using optical spectroscopy: an in vitro study - J Biomedical Optics 5(2): 214-220 (2000).

Pratisto HS, Uhlhorn SR, Jansen ED - Beam delivery of the Vanderbilt Free Electron Laser with hollow wave guides: effect on temporal and spatial pulse propagation - Fiber and Integrated Optics: 20(1): 83-94 (2000).

Ramanujam N, Richards-Kortum R, Thomsen S, Mahadevan-Jansen A, Follen M, Chance B, Low temperature fluorescence imaging of freeze-trapped human cervical tissues, Optics Express, 8(6), 335-343, December 2000.