Dr. Todd Giorgio

Recent publications"

Tseng W, Haselton, FR and Giorgio TD: Mitosis activates transgene expression of plasmid delivered by cationic liposomes. Biochimica Biophysica Acta 1999, 1445, 53-64.

Mehta A, Haselton FR and Giorgio TD: Quantitative estimation of binding sites for cationic liposomes in mammalian endothelial cells. Biochimica Biophysica Acta 1998, [in review].

Tseng W, Haselton, FR and Giorgio TD: Transfection by cationic liposomes using simultaneous single cell measurements of plasmid delivery and transgene expression. Journal of Biological Chemistry 1997, 10 October, 25641-25647.

Montero GA, Giorgio TD and Schnelle KB: Supercritical fluid extraction of contaminated soil. The Journal of Environmental Science and Health 1997,A32, 481-495.

Tseng W, Purvis NB, Haselton FR and Giorgio TD: Cationic liposomal delivery of plasmid to endothelial cells measured by quantitative flow cytometry.  Biotechnology and Bioengineering 1996,50, 548-554.

Montero GA, Giorgio TD and Schnelle KB: Scale-up and economic analysis for the design of supercritical fluid extraction equipment for remediation of soil.  Environmental Progress  1996, 15, 112-121.

Giorgio TD and Yek SH: The effect of bilayer composition on calcium ion transport facilitated by fluid shear stress. Biochimica Biophysica Acta 1995, 1239, 39-44.

Rozga J, Morsiani E, LePage E, Moscioni AD, Giorgio T and Demetriou AA: Isolated hepatocytes in a bioartificial liver: a single group view and experience. Biotechnology and Bioengineering 1994, 43, 645-653.

Purvis NB, Giorgio TD, Stelzer, GT and Shults, KE: Shear-induced platelet activation measured by flow cytometry. Annals of the New York Academy of Sciences 1994, 714, 309-311.

Purvis NB and Giorgio TD: Cell size and surface area determined by flow cytometry. Annals of the New York Academy of Sciences 1994, 714, 306-308.

Tseng W, Haselton, FR and Giorgio TD: Transfection by cationic liposomes using simultaneous single cell measurements of plasmid delivery and transgene expression. Journal of Biological Chemistry 1997, 272, 25641-25647.

Tseng W, Haselton, FR and Giorgio TD: Mitosis activates transgene expression of plasmid delivered by cationic liposomes. Biochimica Biophysica Acta 1999, 1445, 53-64.

James M and Giorgio TD: Nuclear-associated plasmid, but not cell-associated plasmid, is correlated with transgene expression in cultured mammalian cells. Molecular Therapy 2000, 1, 339-346. [Commentary in Leopold PL: Fluorescence methods reveal intracellular trafficking of gene transfer vectors: The light toward the end of the tunnel. Molecular Therapy 2000, 1, 302-303.]

Hallahan DE, Qu S, Geng L, Cmelak A, Chakravarthy A, Martin W, Scarfone C, Giorgio T: Radiation-mediated control of drug delivery. American Journal of Clinical Oncology 2001, 24, 473-480.

Hallahan DE, Geng L, Qu C, Scarfone S, Giorgio T, Donnelly E, Gao X, Clanton J: Integrin-mediated targeting of drug delivery to irradiated tumor blood vessels. Cancer Cell 2003, 3, 63-74.

Pfeiffer S, Zorn GL, Zhang JP, Farley SM, Giorgio TD, Robson SC, Azimzadeh AM and Pierson RN: Hyperacute lung rejection in the pig-to-human model: platelet receptor inhibitors synergistically modulate complement activation and lung injury. Journal of Transplantation 2003, 75, 953-959.

Banks GA, Roselli RJ, Chen R and Giorgio TD: A model for the analysis of nonviral gene therapy. Gene Therapy 2003, 10, 1766-1775.

Smith RA and Giorgio TD: Quantitation and kinetics of CD51 surface receptor expression: implications for targeted delivery. Annals of Biomedical Engineering 2004, 32, 635-644.

Smith RA and Giorgio TD: Cell-based screening: a high throughput flow cytometry platform for identification of cell-specific targeting molecules. Combinatorial Chemistry and High Throughput Screening 2004, 7, 141-151.

Harris SS and Giorgio TD: Convective flow increases lipoplex delivery rate to in vitro cellular monolayers. Gene Therapy 2005, 12, 512-520.

Kuhn SJ, Hallahan DE and Giorgio TD: Characterization of superparamagnetic nanoparticle interactions with extracellular matrix in an in vitro system. Annals of Biomedical Engineering 2006, 34, 51-58.

Kuhn SJ, Finch SK, Hallahan DE and Giorgio TD: Proteolytic surface functionalization enhances in vitro magnetic nanoparticle mobility through extracellular matrix. NanoLetters 2006, 6, 306-312.